CAPVAXIVE (PCV21)

This vaccine protects against pneumococcal disease

Ingredients:

Active ingredients:

Purified sugars from the capsule (outside) of 21 serotypes of Streptococcus pneumoniae (3, 6A, 7F, 8, 9N, 10A, 11A, 12F, 15A, 15B, 15C, 16F, 17F, 19A, 20A, 22F, 23A, 23B, 24F, 31, 33F, and 35B). In order to help the vaccine create an immune response, these sugars are conjugated (attached) to a protein from diphtheria called CRM197 carrier protein.

Inactive ingredients:
Amounts are based on a 0.5 mL dose

Salts: help maintain the stability and pH of the vaccine

Other Stabilizers:

Relevant Terms

Adjuvant: a compound added to some vaccines to strengthen the immune response
Amino Acid: building blocks that make up proteins in the body
Antibody: a protein made by the immune system in response to a foreign particle (antigen). These proteins circulate in the blood and help defend the body against the substance.
Antigen: This is any substance that triggers the immune system to create antibodies. For example, allergens such as pollen are antigens.
Conjugate: Attaching an antigen to a protein in order to improve the protection the vaccine provides.
pH: a measure of how acidic or basic a solution is. The scale ranges from 0 (very acidic) to 14 (very basic). A pH of 7 is neutral.
Serotype: a group of strains within a species that share a particular type of surface structure.
Strain: Within a particular species there can be a lot of genetic diversity. A strain refers to one member of that species. Similarly, every human is genetically a little bit different but still part of the same species.

Sources

Last updated: July 24, 2024